CBD is cannabidiol, a naturally occurring chemical compound found mainly in the Cannabis sativa plant. CBD has been shown to interact with the human endocannabinoid system, or internal cannabinoid system. The human body produces chemicals that are structurally similar to some of the chemicals specific to the cannabis plant. CBD and other cannabinoids can effect receptors sites on the surface of our cells sometimes act as a “key,” and fit into a “lock.” This endocannabinoid system is part of the body’s self regulating system which keeps the body in balance, also known as homeostasis.

The whole of the animal kingdom has an endocannabinoid system, or internal cannabinoid system.  CBD is structurally quite similar to the compounds our bodies produce.  Cannabinoids work on neurotransmitters distributed everywhere in body. The effect of CBD on the endocannabinoid system and its wide distribution throughout the body explains the myriad effects of CBD.  For instance, CBD acts as an anti-inflammatory.  When you consider how many conditions are caused by inflammation, it’s no wonder CBD is touted to treat so many conditions.  CBD also stimulates nerve growth when studied in test tubes outside the body, and there is scientific evidence this also occurs in living subjects with brain injuries.  Tumor cells have been observed to self destruct when exposed to CBD in test tube experiments, and is being studied for its anti-tumor properties.

It is also important to state what CBD will not do.  CBD does not cause intoxication.  Some people report that CBD gives them a sense of well-being, so it’s not really accurate to say that it doesn’t cause any psychoactive effect.  Many, many patients report a sense of greater well-being which is by definition a psychoactive response. In some cases, CBD can cause drowsiness, however, this is certainly not the case for most at the proper dosage – just like any other medication.

The hemp plant produces hundreds of phytocannabinoids that act in concert together creating what’s called an entourage effect. While CBD is the main component, it is but one of the molecules at work. The other types of phytonutrients, such as terpenes (e.g. limonene), essential oils (e.g. lavender), and flavonoids (antioxidants & flavorings) in addition to the other cannabinoids present such as CBN, CBG, CBC account for the way the strain makes a person feel. An analogy is that a soloist needs the other instruments to bring a symphony to life. Isolate can work, but not as well and usually requires a much higher and more expensive dosage.

While it’s true that CBD can effect different people in different ways, CBD does not cause a person to become intoxicated or lose control.  Many people report feeling a sense of well-being, but not a high feeling.  Depending upon brand and compounds in the formulation, there can be mild sedation that can be desirous for sleep issues. There are other compounds that if present can counteract that effect though. Those same uplifting compounds can also be had simply by eating citrus.

Scientific nomenclature is a standardized way to classify and refer to an organism.  In this case, we are referring to the plant Cannabis (the genus) sativa (the species.)  Historically, Western scientists referred to this plant as Cannabis sativa, and today includes both marijuana and hemp. Hemp is a legal definition indicating a subspecies of the Cannabis sativa plant that grows out of the ground with less than 0.3%THC.  Marijuana is the Cannabis sativa plant that contains more than 0.3%THC when it is harvested.

Historically, marijuana was the name given to this plant in central and South America.  Around the 1930’s when the US prohibited cannabis, the term ‘marijuana’  was made popular by federally backed propaganda to induce a negative connotation against the plant and xenophobia against Mexican immigrants in an effort to link the plant with “undesirables.”  Hemp was generally the term for the the plant when used for industrial applications.  Other cultures use other terms to refer to the cannabis plant such as ganga and bhang.

It is possible you will test positive for marijuana on a urine, oral, or blood toxicology test.  Because our CBD extract contains trace amounts of THC, well below the legal 0.3% threshold, you could test positive.  In addition, THC can remain in your body for days to weeks after ingesting it.  The drug tests can’t tell if the compound is causing intoxication (or not) at the time of the test.  The same is true of other substances such as benzodiazepines.

Ontogen prides itself on helping the consumer find their optimal dose.  At Ontogen, we advocate for starting low, and going slow.  It is often reported that a single dose here and there can have benefit, but the optimal benefit is achieved by using CBD extract consistently and starting at a low dose to find the right amount for each individual. The effect typically lasts 8-12 hours, so taking it 2-3 times a day works best.  Most people find they reach a steady state after taking it regularly for 4-5 days.  For this reason, you should continue each dose for at least 4 days before you increase the dose, and increases should be relatively modest.  Your practitioner can help you find your optimal dose.

*Always discuss pregnancy, other supplements and medications you are taking with your practitioner.*

Cannabinoids are known to have a double dose response curve.  This is different from most medications, which have a single dose response curve.  What this means, is that for most medications, the more you take, the stronger it is.  With CBD and other cannabinoids, a low dose may work better than a medium dose, and the low dose may work the same or better than a high dose.

At Ontogen, we know that finding the right dose can help you feel your best and also save you money by avoiding costly higher dosing.

At Ontogen, we strive to provide a consistent product by using a mix of stains in each batch we produce, to obtain an end product that has relative consistency from batch to batch.  Wine makers would call this a “meritage,” a mix of grape, or in this case hemp varieties.  As with all natural products, there will be some variability from crop to crop.  

People sometimes name a variety that consistently has a similar profile of phytocannabinoids and/or its effects on the user, known as a strain name or also called strands.   These phytocannabinoids, such as terpenes, essential oils, and flavonoids in addition to the other cannabinoids present such as CBN, CBG, CBC account for the way the strain makes a person feel.

Be aware, however, that strain names have no clear definition, scientific nomenclature, structural consistency, or oversight.  For these reasons, strain names are not a very accurate connotation of expected effect.

Federally yes provided the THC content is below .3%, which all Ontogen products are.
You as a patient are ultimately responsible for knowing the CBD legality in your state. This is rapidly evolving. For most styyes, or in the process. There are CBD specific allowances only in many states, most are for medical use only. There are 3 specific states that prohibit CBD use that Ontogen will not ship to: Idaho, Nebraska, and South Dakota.

200% Ethanol-extraction which the FDA has classified “Generally Regarded as Safe” and is already used in making many common foods and medicines.

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